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Selected Scientific Publications

For those interested in a more detailed representation of our colleagues' investigations
for various disease indications, we offer the following library of articles.

2005
Yeramian P, Meshnick SR, Krudsood S, Chalermrut K, Silachamroon U, Tangpukdee N, Allen J, Brun R,
Kwiek JJ, Tidwell R, Looareesuwan S (2005)

Efficacy of DB289 in Thai Patients with Plasmodium vivax or Acute, Uncomplicated
Plasmodium falciparum Infections

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Abstract courtesy of The Journal of Infectious Diseases, JID 2005:192 (15 July)

2004
De Souza EM, Lansiaux A, Bailly C, Wilson WD, Hu Q, Boykin DW, Batista MM,
Araujo-Jorge TC, Soeiro MN. (2004)

Phenyl substitution of furamidine markedly potentiates its anti-parasitic activity against
Trypanosoma cruzi and Leishmania amazonensis. Biochem Pharmacol.
Aug 15;68(4):593-600.

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"Reprinted from Biochemical Pharmacology, Vol. 68, De Souza EM, Lansiaux A, Bailly C, Wilson WD,
Hu Q, Boykin DW, Batista MM, Araujo-Jorge TC, Soeiro MN, Phenyl substitution of furamidine
markedly potentiates its anti-parasitic activity against Trypanosoma cruzi and Leishmania amazonensis.
Biochem Pharmacol. 593-600, Copyright (2004), with permission from Elsevier."

Ansede JH, Anbazhagan M, Brun R, Easterbrook JD, Hall JE, Boykin DW. (2004)
O-alkoxyamidine prodrugs of furamidine: in vitro transport and microsomal metabolism as
indicators of in vivo efficacy in a mouse model of Trypanosoma brucei rhodesiense infection.

J Med Chem. Aug 12;47(17):4335-8.
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"Reprinted with permission from the Journal of Medicinal Chemistry.
Copyright 2004 American Chemical Society."

2003
Givens MD, Dykstra CC, Brock KV, Stringfellow DA, Kumar A, Stephens CE, Goker H, Boykin DW. (2003)
Detection of inhibition of bovine viral diarrhea virus by aromatic cationic molecules.
Antimicrob Agents Chemother. Jul;47(7):2223-30.
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This article is courtesy of American Society of Microbiolog

2002
Lansiaux A, Tanious F, Mishal Z, Dassonneville L, Kumar A, Stephens CE, Hu Q, Wilson WD,
Boykin DW, Bailly C. (2002)

Distribution of furamidine analogues in tumor cells: targeting of the nucleus or mitochondria
depending on the amidine substitution.

Cancer Res. Dec 15;62(24):7219-29.
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Boykin DW (2002)
Antimicrobial Activity of the DNA Minor Groove Binders Furamidine and Analogs.
J Braz Chem Soc 13(6):763-771.
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This article is courtesy of Journal of the Brazilian Chemical Society

Del Poeta M, Schell WA, Dykstra CC, Jones SK, Tidwell RR, Kumar A, Boykin DW, Perfect JR. (1998)
In vitro antifungal activities of a series of dication-substituted carbazoles, furans, and benzimidazoles.
Antimicrob Agents Chemother. Oct;42(10):2503-10.
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This article is courtesy of American Society of Microbiology

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